Over many years of research, I have learned a few things concerning wound ballistics. Among these truths is that only actual damage counts for anything. The wound potential of a cartridge depends upon the level of penetration of a bullet and the expansion, if any, of the projectile. Larger bullets make bigger holes. Coupled with the constant of adequate penetration, a larger caliber always has more potential to do damage, cause blood loss, and shut down the adversary’s body.